There is promising news regarding lost pregnancies: low-dose aspirin usage may help women who have previously lost a pregnancy conceive and carry a pregnancy to a full term.
Where Does Aspirin Come Into Play?
Researchers were able to narrow down a subgroup of women who were experiencing high levels of C-reactive protein (CRP), which is a substance found in blood when inflammation is experienced. It is believed that Aspirin counteracts this protein and reduces the inflammation.
Background of the Study
Researchers at NIH’s Eunice Kennedy Silver National Institute of Child Health & Human Development classified women into 3 groups:
• Low CRP (below .70 mg per liter of blood)
• Mid CRP (from .70 to 1.95)
• High CRP (at or above 1.95)
Women within each group received either daily low–dose aspirin or a placebo. In their findings, they found no significant differences in birth rates between those receiving aspirin and those receiving placebo in both the low CRP and mid CRP groups.
However, for the high CRP group, those taking the placebo had the lowest rate of live birth at 44 percent, while those taking daily aspirin had a live–birth rate of 59 percent — a 35–percent increase. Aspirin also appeared to reduce CRP levels in the high CRP group when measured during weeks 8, 20, and 36 of pregnancy.
Based on their results, the researchers are led to believe that Aspirin does in fact play a role in helping those who have lost a pregnancy to conceive & carry a pregnancy to birth. However, it was concluded that further research is necessary to confirm this hypothesis.